Peer-reviewed veterinary case report
Stillborn infant with calcified chorionic epithelium, corneal scarring, and pericarditis.
- Journal:
- Fetal and pediatric pathology
- Year:
- 2009
- Authors:
- Bendon, Robert W & Sebastian, Manu M
- Affiliation:
- Department of Pathology · United States
- Species:
- horse
Plain-English summary
This study looked at a stillborn baby who had several unusual health issues. The baby showed signs of problems with the membranes around the baby and the umbilical cord, as well as brain damage, joint deformities, eyelid issues, heart inflammation, a small left foot, and a cleft palate. The researchers think that these problems might have been caused by an infection that happened earlier in the pregnancy. They compared this case to a condition in horses that also involves infections affecting the baby. Overall, the findings suggest that the baby experienced a serious infection while still in the womb.
Abstract
This autopsy of a stillborn term infant revealed a constellation of unusual features including calcification of the chorion membrane and portions of the umbilical vascular media, extensive white matter gliosis, arthrogryposis multiplex congenita, adhesions of one eyelid to the globe, pericarditis, a miniature left foot, and a cleft palate. We hypothesized that the membrane and umbilical cord lesions resulted from an episode of resolved chorioamnionitis earlier in the pregnancy. Mare reproductive loss syndrome (MRLS) demonstrates a bacteremic infection of the amniotic cavity, pericarditis, and uniocular endophthalmitis in the mare. On the basis of analogy, we speculated that this infant suffered an intrauterine bacteremia with tissue predilection similar to that of MRLS.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19842882/