Peer-reviewed veterinary case report
Stomatocytosis causing low red blood cells in two 12-year-old dogs
By Castillo, Daniel & Williams, Tim L·Published in Veterinary clinical pathology·2021·Department of Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Stomatocytosis in a Beagle and Australian Cattle Dog.
- Species:
- dog
Plain-English summary
A 12-year-old female neutered Australian Cattle Dog and a 12-year-old male neutered Beagle were both diagnosed with a rare blood condition called stomatocytosis, which affects red blood cells. Their blood tests showed a decrease in red blood cell numbers and unusual shapes, but they didn't show signs of severe anemia or other serious symptoms. The dogs were monitored closely, and while the condition raised concerns about their red blood cell membranes, it didn't lead to any immediate health issues. Both dogs were stable and did not require aggressive treatment.
People also search for: dog stomatocytosis symptoms · Beagle blood disorder · Australian Cattle Dog anemia treatment
Abstract
BACKGROUND: Canine stomatocytosis is a well-recognized rare erythrocyte disorder characterized by nonsyndromic forms with selective erythroid involvement, syndromic forms with extra-hematologic disease, and acquired forms. OBJECTIVES: We describe serial clinicopathologic changes in two dogs with stomatocytosis of breeds that are different from those previously reported. METHODS: Blood samples were obtained from a 12-year-old female neutered Australian Cattle Dog and a 12-year-old male neutered Beagle for hematologic and biochemical analyses, including a morphologic examination of peripheral blood films. Serial clinicopathologic data were reviewed, including CBCs performed by the referring veterinary surgeons. RESULTS: Serial CBC data in both cases reported a variable decrease in RBC numbers commonly associated with a normal hematocrit, macrocytosis, hypochromasia, changes in red cell distribution width parameters including marked histogram abnormalities in volume distribution of the RBC population, and mildly increased or normal reticulocyte counts. Morphologic examination of peripheral blood films identified variable numbers of stomatocytes, knizocytes (Case 1, Day 1, Day 4), mild anisocytosis, mild macrocytosis, and mild polychromasia. CONCLUSIONS: In both cases, the changes exhibited in the erythrogram raise suspicion for an RBC membrane disorder with cell volume dysregulation and stomatocytosis, although they did not appear to cause clinically relevant hemolysis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34628677/