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Peer-reviewed veterinary case report

Streptococcus equi bacteriophage SeP9 binds to group C carbohydrate but is not infective for the closely related S. zooepidemicus.

Journal:
Veterinary microbiology
Year:
2009
Authors:
Tiwari, Raksha & Timoney, John F
Affiliation:
Department of Veterinary Science · United States

Abstract

Streptococcus equi (S. equi subsp. equi) is widely believed to have evolved from an ancestral strain of S. zooepidemicus (S. equi subsp. zooepidemicus) based on high sequence homology. A striking difference is the absence of phage sequences from S. zooepidemicus. In this study we show that the receptor for SeP9, a temperate bacteriophage of S. equi, is the Lancefield group C carbohydrate. However, although SeP9 binds to group C carbohydrate from S. zooepidemicus, it appears not to replicate and produce plaques.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18986779/