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Peer-reviewed veterinary case report

Dog with Streptomyces cyaneus skin infection in right armpit

By Nicholls, P K et al.·Published in Australian veterinary journal·2014·School of Veterinary and Life Sciences, Australia·View original on PubMed

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Original publication title: Streptomyces cyaneus dermatitis in a dog.

Species:
dog

Plain-English summary

A nearly 4-year-old neutered male Australian Terrier was brought in for a lump in his right armpit that wasn't getting better with antibiotics. After testing, the vet suspected a specific type of infection and started the dog on a different medication, which helped at first. Unfortunately, the lump came back five months later, and the dog was euthanized after further tests confirmed a rare infection caused by Streptomyces cyaneus. This case highlights that some infections thought to be contaminants can actually be harmful.

People also search for: dog lump under arm · Australian Terrier skin infection treatment · why is my dog not responding to antibiotics

Abstract

BACKGROUND: A nearly 4-year-old neutered male Australian Terrier was referred for a nodular pyogranulomatous mass of the right axilla. It had been poorly responsive to antibiotic therapy. CASE REPORT: Based on filamentous Gram-positive organisms identified in earlier biopsy material, infection by an Actinomyces sp. was suspected and the dog showed clinical improvement on a trial of potentiated sulfonamides. Recurrence 5 months later prompted euthanasia, with Streptomyces cyaneus being cultured and confirmed by genetic sequencing of part of the 16 s ribosomal RNA gene. CONCLUSION: Invasive Streptomyces spp. infections are uncommon in humans and animals, and isolations are sometimes considered to be contaminants, but the demonstration of the organism within the lesion in this instance indicates that the isolation of a Streptomyces sp. from veterinary cases should not always be considered as contamination, because this genus is clearly pathogenic.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24471881/