Peer-reviewed veterinary case report
Studies of distribution and recurrence of Helicobacter spp. gastric mucosa of dogs after triple therapy.
- Journal:
- Acta cirurgica brasileira
- Year:
- 2011
- Authors:
- Anacleto, Thiago Pires et al.
- Affiliation:
- Faculty of Medical Sciences · Brazil
- Species:
- dog
Plain-English summary
In a study involving 20 dogs that tested positive for Helicobacter bacteria, researchers looked at how effective a triple antibiotic treatment was and whether the infection came back. The dogs underwent a procedure called endoscopy to take samples from their stomachs, and they were divided into two groups: one that received treatment with clarithromycin, amoxicillin, and lansoprazole for seven days, and another that was kept away from other dogs. All the treated dogs responded well to the medication, but 80% of those that were in contact with other infected dogs had the infection return after 60 days. The study found that being in crowded situations with other infected dogs increases the chances of spreading Helicobacter among them.
Abstract
PURPOSE: To analyze the triple antimicrobial therapy in positive Helicobacter spp. dogs and to investigate recurrence. METHODS: A total of 20 dogs underwent endoscopy followed by gastric biopsy using the rapid urease test and histopathology stained with Giemsa. Ten animals were treated with triple therapy recommended for humans and divided into control and experimental group. The control group was kept in isolation while the experimental group was placed in contact with positive animals during 60 days. RESULTS: The prevalence of infection in animals in this experiment was 100%, and more frequent in the fundus and the gastric body. Therapy for 7 days using clarithromycin, amoxicillin and lansoprazole was effective in 100% of the animals. Recurrence of the infection in 80% of dogs in the experimental group, while the control group remained eradicated after 60 days. CONCLUSION: Crowded environments associated with close contact with dogs infected with helicobacter are a determinant for transmission of Helicobacter spp. between canines.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21445468/