Peer-reviewed veterinary case report
Helicobacter stomach infection in dogs treated with triple therapy
By Anacleto, Thiago Pires et al.·Published in Acta cirurgica brasileira·2011·Faculty of Medical Sciences, Brazil·View original on PubMed →
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Original publication title: Studies of distribution and recurrence of Helicobacter spp. gastric mucosa of dogs after triple therapy.
- Species:
- dog
Plain-English summary
A group of 20 dogs with a Helicobacter infection underwent endoscopy and gastric biopsy to confirm the diagnosis. They were treated with a 7-day course of antibiotics (clarithromycin and amoxicillin) and a stomach acid reducer (lansoprazole), which successfully cleared the infection in all dogs. However, 80% of the dogs that were in contact with other infected dogs experienced a recurrence of the infection, while those kept isolated remained free of it. This suggests that close contact with infected dogs can lead to reinfection.
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Abstract
PURPOSE: To analyze the triple antimicrobial therapy in positive Helicobacter spp. dogs and to investigate recurrence. METHODS: A total of 20 dogs underwent endoscopy followed by gastric biopsy using the rapid urease test and histopathology stained with Giemsa. Ten animals were treated with triple therapy recommended for humans and divided into control and experimental group. The control group was kept in isolation while the experimental group was placed in contact with positive animals during 60 days. RESULTS: The prevalence of infection in animals in this experiment was 100%, and more frequent in the fundus and the gastric body. Therapy for 7 days using clarithromycin, amoxicillin and lansoprazole was effective in 100% of the animals. Recurrence of the infection in 80% of dogs in the experimental group, while the control group remained eradicated after 60 days. CONCLUSION: Crowded environments associated with close contact with dogs infected with helicobacter are a determinant for transmission of Helicobacter spp. between canines.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21445468/