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Peer-reviewed veterinary case report

Studies on prevalence of Hantavirus in small mammals in Southeast Asia: A systematic review and meta-analysis.

Journal:
PLoS neglected tropical diseases
Year:
2026
Authors:
Guo, Zixiao et al.
Affiliation:
School of Public Health · China

Abstract

BACKGROUND: This study systematically analyzed the prevalence of Hantavirus (HVs) in small mammals across Southeast Asia to evaluate the risks of this zoonotic disease. METHODS: We searched the Web of Science, PubMed, Embase, Scopus, and Cochrane Library for studies published up to 6 February 2025, extracted data from 28 eligible studies. RESULTS: Meta-analysis revealed a pooled prevalence of HVs was 6.07% (986/11,806) in small mammals in Southeast Asia, with the highest prevalence in Indonesia (17.49%) and Singapore (10.53%). The prevalence was higher in samples detected by Enzyme-Linked Immunosorbent Assay (10.68%) and in rodents (8.07%). CONCLUSIONS: The results of our study highlight the urgency of strengthening surveillance in trade networks with Southeast Asia, particularly in high-risk areas such as Indonesia and Singapore, to mitigate the threat of imported zoonotic diseases.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41818286/