Peer-reviewed veterinary case report
Studies on the presence of magnesium in visceral amyloid.
- Journal:
- Zentralblatt fur Pathologie
- Year:
- 1994
- Authors:
- Müller, W & Firsching, R
- Affiliation:
- Institute of Pathology · Germany
- Species:
- horse
Plain-English summary
This study looked at the presence of magnesium in amyloid deposits, which are abnormal protein clumps that can occur in various conditions. The researchers used specific tests to find magnesium in these deposits from different sources, including a pituitary tumor and a case of skin amyloidosis in horses. They found that the amyloid deposits in blood vessels had particularly high levels of magnesium. However, the exact importance of these findings is still not clear, as the researchers are exploring how magnesium interacts with other substances in the body. Overall, the study suggests interesting connections, but more research is needed to understand their significance.
Abstract
The Magneson and Titan yellow tests were used to detect Mg in amyloid deposits in primary and secondary amyloidosis, in a pituitary tumour and in a case of equine cutaneous amyloidosis. Especially vascular amyloid deposits turned out to contain high levels of Mg. The significance of these findings remains unclear at present. Competition between Mg and Ca, the relationship between Mg in elastic fibres and amyloid P-component, and the high water content of amyloid along with the interaction of Mg with water are discussed.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/7826979/