Peer-reviewed veterinary case report
Study on anti-atherosclerotic effect of Suxiao Jiuxin Pill and its mechanism.
- Journal:
- African journal of traditional, complementary, and alternative medicines : AJTCAM
- Year:
- 2014
- Authors:
- Guo, Qing-Xu et al.
- Affiliation:
- The Military General Hospital of BeiJing PLASurgical Dept Vascular Diseases · China
- Species:
- rodent
Abstract
BACKGROUND: Suxiao Jiuxin Pill is composed of Ligusticum wallichii, Borneolum Syntheticum and other drugs; it has qi promoting and blood circulation activating, meridian dredging and pain relieving efficacies. The objective of this paper is to study the effect of Suxiao Jiuxin Pill (quick-acting heart reliever), in atherosclerosis (AS) rat model and explore the mechanism for its prevention and treatment of AS. MATERIALS AND METHODS: AS rat model was established by high cholesterol diet and single intra-peritoneal injection of increased dose of vitamin D3. RESULTS: Compared with the model group, Suxiao Jiuxin Pill medium-and high-dose groups and atorvastatin group can effectively regulate lipid metabolism. CONCLUSION: We conclude that Suxiao Jiuxin Pill has a good hypo-lipidemic effect, and can inhibit the occurrence and development of AS.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24653560/