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Peer-reviewed veterinary case report

Subclinical Scurvy in the Guinea Pig

Journal:
Veterinary Pathology
Year:
1980
Authors:
Clarke, G. L. et al.
Affiliation:
Comparative Pathology Section and Small Animal Section, Veterinary Resources Branch, Division of Research Services, National Institutes of Health, Bethesda, Md.
Species:
rodent

Abstract

Twenty-eight guinea pigs from nine episodes of subclinical scurvy had diarrhea, weight loss and dehydration. The classical signs of scurvy were not seen. Microscopically the epiphyses were attenuated and irregular. The amount of osteoid was less than normal. Many guinea pigs had acute enteritis. In some there were many hemosiderin-laden macrophages in the intestinal lamina propria. All episodes were associated with either autoclaving food without adequate supplementation or other inadequate feed management practices.

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Original publication: https://doi.org/10.1177/030098588001700104