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Peer-reviewed veterinary case report

Horse with kidney injury from silver maple leaves treated

By Pinnell, Erin F et al.·Published in Journal of veterinary internal medicine·2024·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Successful hemodialysis treatment of a Quarter Horse mare with silver maple leaf toxicity and acute kidney injury.

Species:
horse

Plain-English summary

A Quarter Horse mare was brought in showing signs of lethargy and dark-colored urine after eating silver maple leaves, which can be toxic and cause kidney damage. She was treated with a blood transfusion, IV fluids, antibiotics, and oxygen, but her kidney issues didn't improve with standard care. The veterinarians decided to try hemodialysis, a procedure that helps filter toxins from the blood. After two sessions over three days, her kidney function improved significantly, and she was able to go home. Six months later, follow-up tests showed her kidney values were normal.

People also search for: horse silver maple leaf toxicity · Quarter Horse kidney treatment · hemodialysis for horses · horse lethargy dark urine · horse blood transfusion recovery

Abstract

An adult American Quarter Horse mare presented for pigmenturia and lethargy of 12 hours' duration and was diagnosed with silver maple leaf toxicity. The mare had intravascular hemolysis and azotemia. The mare was treated with a transfusion of whole blood, fluids administered IV, antibiotics, oxygen insufflation, and supportive care. The azotemia persisted despite conventional medical management and hemodialysis was elected. After 2 intermittent hemodialysis treatments over 3 days, the azotemia almost resolved, clinical signs improved, and the mare was discharged. The blood urea nitrogen, creatinine, and electrolyte concentrations remained normal 6 months later after examination by the referring veterinarian. Hemodialysis treatment can be feasible in horses if equipment and expertise are available and should be considered as a treatment option if indicated.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38682859/