Peer-reviewed veterinary case report
Dog with adrenal tumor treated successfully by ethanol injection
By Furusato, Shimon et al.·Published in Veterinary medicine and science·2024·Shinagawa WAF Animal Hospital, Japan·View original on PubMed →
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Original publication title: Successful laparotomic ethanol ablation for an adrenal tumour in a dog.
- Species:
- dog
Plain-English summary
A 13-year-old female toy poodle was brought in for severe blood in her urine and was diagnosed with tumors on her left adrenal gland and right kidney. Because of her age and health risks, the veterinarian performed a procedure using ethanol to shrink the adrenal tumor instead of traditional surgery. After the treatment, her cortisol levels returned to normal within eight days, and she showed no signs of hypercortisolism (Cushing's disease) for a year. Unfortunately, she later passed away from kidney failure, but the treatment successfully reduced the size of the tumor.
People also search for: dog adrenal tumor treatment · toy poodle blood in urine · Cushing's disease alternative treatment
Abstract
Adrenalectomy is the gold standard for canine adrenal tumours, but not always recommended due to patient age, underlying conditions and perioperative mortality. Ethanol ablation is an alternative in human medicine for poor surgical candidates. A 13-year-old neutered female toy-poodle with hypercortisolism presented with severe haematuria. Ultrasonography revealed left adrenal and right kidney tumours. Due to high surgical risk, simultaneous laparotomic right nephroureterectomy and ethanol ablation of the left adrenal tumour were performed. Post-ethanol injection complications included transient hypertension and arrhythmia, which resolved spontaneously. The adrenal tumour size decreased within 2.5 months, and cortisol levels normalised within 8 days, remaining stable for 12 months. No hypercortisolism signs were observed without trilostane until death from renal insufficiency. Autopsy showed that the ablated left adrenal gland was an adrenocortical tumour and had shrunk. Ethanol ablation may be a feasible alternative to adrenalectomy for high-risk canine patients.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39287218/