Peer-reviewed veterinary case report
Feline pemphigus foliaceus treated with pentoxifylline and topical
By Stefan Hobi et al.·Published in Veterinary Medicine and Science·2022·Department of Veterinary Clinical Sciences Jockey Club College of Veterinary Medicine and Life Sciences City University Kowloon Hong Kong China, GB·View original on DOAJ →
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Original publication title: Successful management of feline pemphigus foliaceus with pentoxifylline and topical hydrocortisone aceponate
- Species:
- cat
Plain-English summary
A 5-year-old domestic shorthair cat was diagnosed with pemphigus foliaceus, an autoimmune skin condition that causes painful sores and crusting. Instead of the usual high doses of oral medications, the veterinarian treated the cat with a combination of topical hydrocortisone aceponate and pentoxifylline, which helped reduce inflammation and improve the cat's skin condition. The cat responded well to this treatment, showing significant improvement without the need for invasive procedures like a biopsy.
People also search for: cat skin problems treatment · pemphigus foliaceus in cats · topical hydrocortisone for cats
Abstract
Abstract The treatment regimen for feline pemphigus foliaceus (PF), an autoimmune disease caused by auto‐antibodies against proteins of the desmosome junction, usually includes high doses of oral or parenteral immunosuppressive drugs, typically glucocorticoids. This case adds to a growing body of evidence that topical hydrocortisone aceponate is effective for the treatment of feline PF, and demonstrates the practical use of a non‐invasive diagnostic method for histopathology when owners refuse a biopsy to support a clinical diagnosis of PF. Finally, this case highlights an international trend of owner‐initiated treatment of feline infectious peritonitis (FIP) using unlicensed, unregistered drugs.
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Search related cases →Original publication on DOAJ: https://doi.org/10.1002/vms3.768