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Peer-reviewed veterinary case report

Dog with gut pythiosis cured using itraconazole terbinafine

By Hummel, James et al.·Published in Medical mycology·2011·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam.

Species:
dog
Canine giardiasisStomach & digestionDogs

Plain-English summary

A dog with gastrointestinal pythiosis, a serious infection caused by a water mold, was successfully treated with a combination of medications including itraconazole, terbinafine, and mefenoxam. The treatment led to the resolution of the dog's lesions without significant side effects. This case highlights the potential effectiveness of these drugs in managing this challenging condition in dogs.

People also search for: dog gastrointestinal pythiosis treatment · itraconazole for dogs · mefenoxam side effects in pets

Abstract

Medical therapy for pythiosis is hampered by a lack of efficacious drugs. The present report describes a case of canine gastrointestinal pythiosis in which lesions were resolved through the administration of itraconazole, terbinafine, and the agricultural fungicide mefenoxam. No substantial adverse effects occurred in association with administration of the latter compound. Additional studies are needed to evaluate the pharmacokinetics of mefenoxam and to further assess its tolerability and potential efficacy for the treatment of pythiosis in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21174493/