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Peer-reviewed veterinary case report

Boxer dogs with ulcerative colitis treated successfully

By Davies, D R et al.·Published in Australian veterinary journal·2004·Murdoch University, Australia·View original on PubMed

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Original publication title: Successful management of histiocytic ulcerative colitis with enrofloxacin in two Boxer dogs.

Species:
dog

Plain-English summary

Two Boxer dogs were diagnosed with a serious bowel condition called histiocytic ulcerative colitis, which can cause severe diarrhea and discomfort. After standard treatments didn't work, they were given a medication called enrofloxacin. Both dogs showed quick improvement, with one even having normal results on a follow-up colonoscopy just two weeks later. After seven months, the dog's bowel tissue showed no signs of the disease, marking a successful outcome for this treatment approach.

People also search for: Boxer dog diarrhea treatment · histiocytic ulcerative colitis in dogs · enrofloxacin for dog bowel issues

Abstract

Two Boxer dogs with histologically confirmed histiocytic ulcerative colitis were treated with enrofloxacin, one as sole therapy and one in conjunction with prednisolone, after failure of standard therapy. Clinical remission occurred rapidly in both dogs after commencement of enrofloxacin and in one case where repeat colonoscopy was performed the endoscopic appearance of the mucosa was normal within 2 weeks. Histological examination of the colonic mucosa in this dog after 7 months showed resolution of the cellular infiltration characteristic of histiocytic ulcerative colitis. Histological improvement following therapy in Boxer dogs with histiocytic ulcerative colitis has not been reported previously.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15088960/