Peer-reviewed veterinary case report
Dog with drug-resistant Pseudomonas pneumonia after kidney transplant
By Park, Kyung-Mee et al.·Published in The Journal of veterinary medical science·2013·College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Successful management of multidrug-resistant Pseudomonas aeruginosa pneumonia after kidney transplantation in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old male mongrel dog developed an acute cough, loss of appetite, and trouble exercising just 25 days after having a kidney transplant. Tests showed he had pneumonia caused by a tough-to-treat bacteria called multidrug-resistant Pseudomonas aeruginosa. Initially, two broad-spectrum antibiotics didn’t help, but after switching to a specific antibiotic called imipenem-cilastatin, his symptoms completely went away without changing his other medications. He remained healthy with no signs of pneumonia returning during a 2-year follow-up.
People also search for: dog cough after kidney transplant · pneumonia treatment for dogs · multidrug-resistant bacteria in dogs
Abstract
An 8-year-old male mongrel dog that had undergone renal transplantation was presented 25 days later with an acute cough, anorexia and exercise intolerance. During the investigation, neutrophilic leukocytosis was noted, and thoracic radiographs revealed caudal lung lobe infiltration. While being treated with two broad-spectrum antibiotics, clinical signs worsened. Pneumonia due to infection with multidrug-resistant (MDR) Pseudomonas (P.) aeruginosa, sensitive only to imipenem and amikacin, was confirmed by bacteria isolation. After treatment with imipenem-cilastatin without reducing the immunosuppressant dose, clinical signs completely resolved. During the 2-year follow-up period, no recurrence was observed. To the best of authors' knowledge, this is the first report of pneumonia caused by MDR P. aeruginosa in a renal recipient dog and successful management of this disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23842146/