Peer-reviewed veterinary case report
Dog with non-responsive gut disease improves after one fecal
By Sugita, Koji et al.·Published in The Journal of veterinary medical science·2021·Cooperative Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Successful outcome after a single endoscopic fecal microbiota transplantation in a Shiba dog with non-responsive enteropathy during the treatment with chlorambucil.
- Species:
- dog
Plain-English summary
A 7-year-old Shiba dog was brought in after suffering from lethargy, loss of appetite, vomiting, and frequent watery diarrhea for a month. The vet found that the dog had lost weight and had low protein levels, anemia, and high white blood cell counts. After diagnosing the dog with non-responsive enteropathy (a serious gut issue), they tried a fecal microbiota transplantation (FMT) along with a medication called chlorambucil. This treatment significantly improved the dog's symptoms and overall health, with no side effects or return of the issues.
People also search for: Shiba dog diarrhea treatment · fecal microbiota transplantation for dogs · dog vomiting and diarrhea causes
Abstract
A 7-year 6-month-old, castrated male Shiba dog presented with a 1-month history of lethargy, anorexia, vomiting, and frequent watery diarrhea. Weight loss, hypoalbuminemia, anemia, and leukocytosis were detected at the first visit. The dog was diagnosed with non-responsive enteropathy (NRE) based on clinical and histopathological examinations. Since the dog did not respond to the immunosuppressive drugs, fecal microbiota transplantation (FMT) was performed during the treatment with chlorambucil. A single endoscopic FMT into the cecum and colon drastically recovered clinical signs and clinicopathological abnormalities and corrected dysbiosis in the dog. No recurrence or adverse events were observed. The present case report suggests that FMT, possibly together with chlorambucil, might be a treatment option for NRE in Shiba dogs that have poorer prognosis compared with other dog breeds.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33896875/