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Peer-reviewed veterinary case report

Successful treatment of a metastatic, gastrointestinal stromal tumour in a dog with toceranib phosphate (Palladia).

Journal:
The Journal of small animal practice
Year:
2017
Authors:
Elliott, J W et al.
Affiliation:
Willows Referral Service
Species:
dog

Abstract

A ten-year-old, female-entire English springer spaniel presented with a large intra-abdominal mass but no other clinical signs. Gastrointestinal stromal tumour of the caecum with widespread abdominal metastasis was confirmed. Treatment with toceranib phosphate resulted in complete response, despite the absence of exon-8 or exon-11 c-kit mutation. There was no clinical evidence of tumour recurrence nine months after diagnosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28199021/