Peer-reviewed veterinary case report
Dog with diarrhea and fluid buildup treated with placenta extract
By Fukushima, Naoki et al.·Published in Open veterinary journal·2022·Panda Animal Hospital, Japan·View original on PubMed →
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Original publication title: Successful treatment of ascites accumulation and diarrhea associated with protein-losing enteropathy with oral equine placenta extract supplementation in a dog: A case report.
- Species:
- dog
Plain-English summary
An 8-year-old female Chihuahua was brought to the vet with diarrhea and fluid buildup in her abdomen (ascites) that had lasted for two weeks. After diagnosing her with protein-losing enteropathy (PLE), the vet initially treated her with medications, but her condition didn’t improve and she developed liver damage. Eventually, they added equine placenta extract to her treatment plan, which helped her recover. After adjusting her medications, the dog showed no further signs of diarrhea or fluid buildup, indicating a successful outcome.
People also search for: Chihuahua diarrhea treatment · dog ascites causes · protein-losing enteropathy in dogs · equine placenta extract for dogs
Abstract
BACKGROUND: Protein-losing enteropathy (PLE) is characterized by leakage of serum proteins into the intestinal lumen, indicating hypoproteinemia. Immunosuppressive agents are the mainstay of treatment, but in many cases, patients are forced to taper off early owing to the induction of liver damage. CASE DESCRIPTION: An 8-year-old, non-spayed female Chihuahua presented with diarrhea and ascites effusion lasting 2 weeks. Based on the results of radiography and blood tests, a diagnosis of PLE was made. Prednisolone (3 mg/kg[SID]) and MitoMax (200 mg/day) were administered, but ascites accumulation and diarrhea did not improve. Thus, azathioprine (2 mg/kg/day) was added, but there was no improvement, and liver damage developed. The liver injury did not improve immediately, but diarrhea and ascites effusion improved after serum total protein and serum albumin levels increased after they had decreased. Subsequent tapering of prednisolone from 3 mg/kg SID to 1 mg/kg SID, combined with MitoMax (200 mg/day) and equine placenta extract (eqPE) (2 ml/day), resulted in no recurrence of ascites or diarrhea. CONCLUSION: In canine PLE with prolonged diarrhea and ascites effusion, supplementation with eqPE may be considered a reasonable additional therapeutic strategy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36589412/