Peer-reviewed veterinary case report
Radiation therapy helped a cat with pituitary tumor and hormone
By Yayoshi, Naoko et al.·Published in The Journal of veterinary medical science·2022·School of Veterinary Science, Japan·View original on PubMed →
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Original publication title: Successful treatment of feline hyperadrenocorticism with pituitary macroadenoma using radiation therapy: a case study.
- Species:
- cat
Plain-English summary
A 10-year-old male cat was brought in for behavioral issues like irritation and prowling, along with skin problems that made his skin fragile. He was diagnosed with hyperadrenocorticism (Cushing's disease) caused by a pituitary tumor and also had diabetes. Initial treatment with medication didn't help, so the vet started radiation therapy. After the treatment, the tumor shrank significantly, and the cat's neurological and skin symptoms improved, showing that radiation therapy was effective for his condition.
People also search for: cat Cushing's disease treatment · cat skin problems · radiation therapy for cat tumor · hyperadrenocorticism in cats · cat diabetes management
Abstract
A 10-year-old castrated male cat showing behavioral (irritation, prowling, and tumbling) and cutaneous abnormalities such as dermal fragility was diagnosed as hyperadrenocorticism with pituitary macroadenoma, concurrent with insulin dependent diabetes mellitus. Pituitary enlargement (18.0 mm) was observed during magnetic resonance imaging. High endogenous adrenocorticotropic hormone levels (>2,500 pg/ml) were also observed. Although trilostane treatment (5-10 mg/head, daily) was commenced, the clinical signs did not disappear. Insulin and trilostane treatment were discontinued on day 86 after first day of radiation therapy (4 Gy/12 fractions). After radiation therapy, a decreased pituitary tumor size (10.7 mm) was observed on day 301; neurological and dermatological signs exhibited remission. Radiation therapy is the treatment of choice for feline hyperadrenocorticism with pituitary macroadenoma with neurological signs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35527017/