Peer-reviewed veterinary case report
Toy poodle vomiting and lethargic after ibuprofen treated with blood
By Ahn, Woonchan et al.·Published in The Journal of veterinary medical science·2026·Signature Animal Medical Center, South Korea·View original on PubMed →
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Original publication title: Successful treatment of ibuprofen intoxication using hemoperfusion with porous polymeric adsorbents in a toy poodle.
- Species:
- dog
Plain-English summary
A 6-month-old female toy poodle was brought to the vet after she started vomiting and seemed very tired because she had eaten ibuprofen. The vet used a special treatment called hemoperfusion, which helped remove the ibuprofen from her blood. After a couple of hours, the amount of ibuprofen in her system dropped significantly, and she began to feel much better. Thankfully, she made a full recovery without needing any more treatment.
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Abstract
A 6-month-old female toy poodle, weighing 2.15 kg, presented with acute vomiting and lethargy after ingesting ibuprofen. Hemoperfusion was performed using an extracorporeal blood purification cartridge, comprising polystyrene-divinylbenzene copolymer beads, connected to a hemodialysis platform as a pre-dialyzer. Serum ibuprofen concentration, measured using high-performance liquid chromatography, was 61.9 mg/L before therapy. The ibuprofen concentrations gradually decreased, reaching 20.5 mg/L after 2 hr (66.8% reduction; half-life of 1.4 hr). The dog showed significant improvement in vitality and recovered fully without further extracorporeal treatment. This case is the first documented instance of successfully treating ibuprofen intoxication in a small dog using hemoperfusion with a blood purification cartridge specifically designed for small animals.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41581905/