Peer-reviewed veterinary case report
Treatment of intestinal malakoplakia in a French Bulldog with diarrhea
By Namiki, Keita et al.·Published in The Journal of veterinary medical science·2024·North lab, Japan·View original on PubMed →
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Original publication title: Successful treatment of intestinal malakoplakia in a French Bulldog.
- Species:
- dog
Plain-English summary
A 5-month-old spayed female French Bulldog was brought to the vet due to chronic diarrhea and bloody mucus in her stool. Despite initial treatments not helping, further tests revealed a rare condition called colonic malakoplakia, which involves inflammation in the intestines. The dog was treated with enrofloxacin, an antibiotic, and showed significant improvement after two months, eventually achieving complete recovery after eight months of treatment.
People also search for: French Bulldog diarrhea treatment · dog blood in stool causes · colonic malakoplakia in dogs · enrofloxacin for dogs · dog intestinal inflammation treatment
Abstract
Malakoplakia is a rare granulomatous inflammation that has mainly been reported in the urinary bladder of dogs. Only one case of canine colonic malakoplakia has been reported to date; however, successful treatment of this disease has not been reported. Here, we report a case of colonic malakoplakia in a 5-month-old spayed female French Bulldog. The dog was referred to a veterinarian because of chronic diarrhea and mucinous blood feces; empirical treatment did not improve its condition. Histologically, numerous macrophages containing periodic acid-Schiff-positive granules infiltrated the lamina propria of the large intestine. Furthermore, targetoid basophilic inclusion bodies (Michaelis-Gutmann bodies) were observed. Complete clinical remission was achieved after 8 months of enrofloxacin treatment and favorable progress after 2 months of medication.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39111849/