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Peer-reviewed veterinary case report

Kitten with bladder infection and malakoplakia treated successfully

By Rutland, Bronwyn E et al.·Published in Journal of feline medicine and surgery·2013·Southpaws Specialty Surgery for Animals, Australia·View original on PubMed

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Original publication title: Successful treatment of malakoplakia of the bladder in a kitten.

Species:
cat

Plain-English summary

A 4-month-old female kitten was brought to the vet with ongoing urinary issues and was found to have a bladder infection caused by E. coli. After further testing, she was diagnosed with a rare condition called malakoplakia, which involves abnormal tissue reactions in the bladder. The kitten was treated with a long course of antibiotics, and thankfully, her condition improved, and the malakoplakia resolved. This case marks the first successful treatment of this unusual condition in a pet.

People also search for: kitten urinary problems · bladder infection treatment in cats · malakoplakia in cats · chronic urinary tract infection in kittens

Abstract

A 4-month-old female kitten presented with chronic lower urinary tract signs and Escherichia coli cystitis, and was diagnosed with urinary bladder malakoplakia based upon histopathology. The kitten was treated with a prolonged antibiotic course and the malakoplakia resolved. Malakoplakia is a chronic granulomatous reaction characterized by the formation of Michaelis-Gutman bodies within von Hansemann macrophages. It is well described in humans, but has never been documented in a living veterinary patient. This case report describes the first successful treatment of malakoplakia in veterinary medicine.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23300187/