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Peer-reviewed veterinary case report

Dog with severe endocrine disease cured of demodicosis by one

By Morita, Tatsushi et al.·Published in The Journal of veterinary medical science·2018·Department of Veterinary Pathobiology, Japan·View original on PubMed

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Original publication title: Successful treatment of refractory demodicosis and transient papules with a single dose of fluralaner in a dog with uncontrolled severe endocrine disease.

Species:
dog

Plain-English summary

A 12-year-old female Shih-Tzu with severe hormonal issues developed a stubborn skin condition called demodicosis, which didn't improve with standard treatments. After trying various medications, including one that had to be stopped due to diabetes, the dog's skin condition worsened again. However, a single dose of fluralaner successfully cleared up the demodicosis completely. While some temporary red bumps appeared on her skin a few days later, there were no serious side effects, showing that fluralaner can be an effective option for treating this skin problem in dogs.

People also search for: dog skin problems treatment · Shih-Tzu demodicosis · fluralaner for dogs · dog diabetes management · dog hormonal issues skin condition

Abstract

A 12-year-old female Shih-Tzu with hyperadrenocorticism and hypothyroidism developed concurrent refractory generalized demodicosis that did not respond to doramectin treatment. Although amitraz treatment was effective, the dog developed severe diabetes, which resulted in the cessation of amitraz and trilostane. Attempts to control the diabetes were unsuccessful, and its hyperadrenocorticism was left untreated, leading to the recurrence of demodicosis. However, demodicosis went into complete remission with a single dose of fluralaner. Transient erythematous papules appeared on the trunk three days after the administration of fluralaner, but no other adverse reactions were noted. We demonstrated that fluralaner is a potent treatment for demodicosis, and skin eruptions are possible after the first dose of the drug.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29515061/