Peer-reviewed veterinary case report
Secnidazole single-dose treatment for giardiosis outbreak in shelter
By Cheung, Wesley et al.·Published in Veterinary parasitology·2019·Sydney School of Veterinary Science, United Kingdom·View original on PubMed →
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Original publication title: Successful use of secnidazole to manage a giardiosis outbreak in a shelter.
- Species:
- dog
Plain-English summary
A group of dogs in a shelter experienced an outbreak of giardiosis, a common intestinal parasite infection. Adult dogs treated with a single dose of secnidazole showed complete recovery within 13 days, while most puppies (9 out of 10) improved significantly after receiving two doses spaced two weeks apart. No side effects were reported from the treatment. This study suggests that secnidazole is a safe and effective option for managing giardiosis in dogs of all ages.
People also search for: dog giardiosis treatment · puppy diarrhea medication · secnidazole for dogs · shelter dog parasite outbreak · giardia symptoms in dogs
Abstract
Giardia duodenalis is a common parasite in dogs in shelters where new introductions, including numerous juvenile individuals, are ongoing. A safe and effective single dose parasiticide is highly desirable for shelters experiencing disease caused by G. duodenalis (giardiosis). Secnidazole is an efficacious, low-cost medication used for the treatment of giardiosis in humans and has the advantage of requiring only a single oral dose. The aim of this study was to determine retrospectively the effectiveness of secnidazole on dogs of all ages during an outbreak of giardiosis in a shelter. Patients recruited into this retrospective study were divided into two groups. Group A consisted of adult dogs and weaned dogs (>10 weeks-of-age). Group B was comprised of puppies (<10 weeks-of-age). Giardiosis resolved in all 14 patients in Group A within 13 days following a single oral dose of secnidazole (30 mg/kg). There were no individuals with both gastrointestinal signs and a positive G. duodenalis antigen test at the time of the first and second follow-up examination. For the young puppies in Group B, giardiosis was reduced by 90% (9/10) within 22 days following two consecutive doses of secnidazole (30 mg/kg; 2 weeks apart). No adverse reactions were observed in any patients treated with secnidazole. Secnidazole is an effective and easily administered drug for the treatment of clinical canine giardiosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31499401/