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Peer-reviewed veterinary case report

Super-sentinel chickens and detection of low-pathogenicity influenza virus.

Journal:
Emerging infectious diseases
Year:
2007
Authors:
Marcus, Philip I et al.
Affiliation:
Department of Molecular and Cell Biology · United States

Abstract

Chicken interferon-alpha administered perorally in drinking water acts on the oropharyngeal mucosal system as an adjuvant that causes chickens to rapidly seroconvert after natural infection by low-pathogenicity Influenza virus. These chickens, termed super sentinels, can serve as sensitive early detectors of clinically inapparent infections.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18258021/