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Peer-reviewed veterinary case report

Corneal cancer treated with surgery and eye drops in a dog

By Karasawa, K et al.·Published in The Journal of small animal practice·2008·Graduate School, Japan·View original on PubMed

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Original publication title: Superficial keratectomy and topical mitomycin C as therapy for a corneal squamous cell carcinoma in a dog.

Species:
dog

Plain-English summary

A 10-year-old female West Highland white terrier was brought to the vet with a rough, raised spot on her left eye that had been getting worse for a month. After examining her, the vet found that the spot was a type of cancer called squamous cell carcinoma. The vet surgically removed the cancerous growth and then treated her with eye drops containing mitomycin C, a chemotherapy drug, for two months. The combination of surgery and medication worked well, and the dog had a good recovery.

People also search for: dog eye cancer treatment · West Highland terrier corneal squamous cell carcinoma · mitomycin C for dogs eye problems

Abstract

A 10-year-old female West Highland white terrier was presented with refractory hyperplastic keratitis of the left cornea of one month's duration. At this time, a vascularised and rough lesion 5 mm in diameter was observed on the left cornea. No other abnormality was recognised on the affected eye. The corneal neoplasm was surgically removed and histologically diagnosed as a squamous cell carcinoma. For two months after the surgery, 0.04 percent mitomycin C (MMC) eye drops were applied as adjuvant chemotherapy. Primary corneal squamous cell carcinoma with no history of keratoconjunctivitis sicca is rare in dogs. In the present report, surgical removal of the neoplasm was combined with the topical administration of the anticancer drug mitomycin C and a good prognosis was obtained. The result indicates that the combination treatment used in this case may be an appropriate therapeutic choice for corneal squamous cell carcinoma in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17725585/