Peer-reviewed veterinary case report
Radiation treatment for mast cell tumors on the head in dogs and cats
By T. Martin et al.Ā·Published in Journal of the American Veterinary Medical AssociationĀ·2023Ā·View original on Semantic Scholar ā
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Original publication title: Superficial kilovoltage x-ray radiotherapy for the treatment of cutaneous mast cell tumors on the head in three dogs and one cat: a limited retrospective case series.
- Species:
- dog
Plain-English summary
A 7-year-old dog with a cutaneous mast cell tumor (a type of skin cancer) on its head received superficial radiation therapy to treat the tumor. Three dogs and one cat were treated in total, and while one dog had to stop treatment due to the cancer spreading, the other three completed their therapy and showed complete tumor response. Two of the dogs also received an additional medication called toceranib. The pets experienced only mild side effects from the treatment, and there were no harmful effects to their eyes.
People also search for: dog skin cancer treatment Ā· cat mast cell tumor radiation therapy Ā· toceranib for dogs with cancer
Abstract
OBJECTIVE To report preliminary findings of hypofractionated superficial radiotherapy for treatment of cutaneous mast cell tumors (MCTs) and report the acute and late toxicity associated with its use. ANIMALS 3 dogs and 1 cat. PROCEDURES In this retrospective study, medical records from January 2021 through July 2022 were searched for animals that received superficial radiation therapy for MCTs of the head. RESULTS 4 patients with 5 MCTs were included. Three of the masses were periocular and required protection of the globe with a tungsten eye shield. One patient did not complete the intended protocol due to diffuse metastatic spread noted after the second fraction. Of the 3 patients that completed their protocol, 100% had a complete response. Two canine patients were treated adjunctively with toceranib. Two of the 4 patients experienced grade 1 acute veterinary radiation therapy oncology group (VRTOG) toxicity, and the 3 patients that completed their protocol experienced grade 1 late VRTOG toxicity. No radiation effects were documented to the cornea or lens in any patient. CLINICAL RELEVANCE Superficial radiation therapy was effective in our limited study population, and patients experienced minimal side effects for treatment of cutaneous MCTs.
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Search related cases āOriginal publication on Semantic Scholar: https://www.semanticscholar.org/paper/37116878