Peer-reviewed veterinary case report
Surgical management of primary, metastatic and recurrent anal sac adenocarcinoma in the dog: 52 cases.
- Journal:
- The Journal of small animal practice
- Year:
- 2017
- Authors:
- Barnes, D C & Demetriou, J L
- Affiliation:
- Dick White Referrals · United Kingdom
- Species:
- dog
Plain-English summary
This study looked at 52 dogs with anal sac adenocarcinoma, a type of cancer that can occur in the glands near the anus. The researchers wanted to see how well surgery worked as a first treatment and how often complications happened. They found that some dogs had minor issues after surgery, and a few needed more surgery later on. Unfortunately, about 12% of the dogs had their cancer come back, and 42% developed cancer in nearby lymph nodes. Overall, if a second surgery was needed due to recurrence, dogs lived an average of about 283 more days. The findings suggest that surgery to remove affected lymph nodes can be safe and beneficial for these dogs.
Abstract
OBJECTIVES: To report the outcomes and complications of a cohort of dogs with primary and recurrent anal sac adenocarcinoma managed with surgery as the first-line treatment. To report the use of lymph node cytology for identification of metastatic disease. METHODS: Retrospective review of case records of a single referral centre population of dogs diagnosed with anal sac adenocarcinoma. RESULTS: Fifty-two clinical cases were identified. Altered ultrasonographic appearance of lymph nodes was highly consistent with metastatic disease as assessed by cytology and histopathology. Seven of 58 (12%) perineal surgeries had reported minor complications and seven (12%) others required further surgical intervention. Minor controllable intraoperative bleeding was the only complication noted associated with lymph node extirpation in two of 39 (5%) metastectomy procedures. Six dogs (12%) suffered local recurrence and 22 (42%) developed subsequent or recurrent nodal metastatic disease. From the time of detection of disease recurrence, median additional survival associated with a second surgical intervention was 283 days. CLINICAL SIGNIFICANCE: Coeliotomy for lymph node metastatectomy in dogs with adenocarcinoma of the anal sac has low morbidity and should be considered in patients presenting with evidence of regional metastatic disease both at initial presentation and with recurrent disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28245066/