Survival following intentional overdose of veterinary insulin: A case report

Abstract

A 40-year-old man presented to the emergency department within 6 h of a massive overdose of 500 units of long-acting feline glargine insulin intravenously and an estimated 50 mg of clozapine. Upon initial assessment, his Glasgow Coma Scale (GCS) was 15 and his blood sugar level was 45 mg/dL. The patient was successfully managed with dextrose infusions and close monitoring of blood sugar and electrolytes. To date, no cases have been documented in the literature describing an overdose of insulin formulation intended for veterinary use. Cases of overdose with animal-prescribed human insulin analogs can be managed similarly to previously reported cases of human insulin overdose.