Peer-reviewed veterinary case report
Survival times and outlook for dogs with haemangiosarcoma in UK
By Taylor, Collette et al.·Published in PloS one·2025·Department of Pathobiology and Population Science, United Kingdom·View original on PubMed →
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Original publication title: Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice.
- Species:
- dog
Plain-English summary
A group of dogs diagnosed with a type of cancer called haemangiosarcoma (a cancer of blood vessels) were studied to understand their survival times and factors affecting their prognosis. On average, these dogs lived about 9 days after diagnosis, with only 12% surviving a year. Dogs with skin tumors had a better outlook, living around 119 days, while those with tumors on the spleen had a much shorter survival of just 4 days. The study suggests that the perceived poor prognosis may lead to premature euthanasia, which could be affecting survival rates.
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Abstract
Visceral haemangiosarcoma is considered clinically aggressive in dogs, with perceived poor prognosis often leading to euthanasia at presentation. This study aimed to determine survival times and prognostic factors in dogs with haemangiosarcoma under first-opinion care. Dogs clinically diagnosed with haemangiosarcoma in first-opinion practice in 2019 were identified in VetCompass electronic health records and examined to capture variables potentially associated with survival. Median survival time (MST) from diagnosis was calculated for the whole population, those histopathologically confirmed and based on primary tumour location. Binary logistic regression was used to explore differences between dogs that died on the day of diagnosis and those that survived ≥1 day. Cox proportional hazards modelling explored factors associated with time to death in dogs surviving ≥1 day. Across all cases (n = 788), overall MST was 9.0 days (95%CI:5.0-15.0, range: 0-1789) and proportional 1-year survival was 12.0% (95%CI:9.7-15.0%). Dogs with splenic (MST = 4.0 days, 95%CI 0.0-9.0) and cutaneous haemangiosarcoma (MST = 119.0 days,95%CI:85.0-248.0) had MST greater than 0 days. Of dogs with a histopathological diagnosis of haemangiosarcoma, overall MST was longer at 105 days (95% CI 84-133 days) and additionally, location-specific MST were longer. For both clinically diagnosed cases and histopathologically confirmed cases, increasing tumour size was associated with increased hazard of death while cutaneous location and surgery were associated with reduced hazard of death. A very short survival time was identified for haemangiosarcoma under first-opinion care. Although survival time was longest for cutaneous cases, the actualised prognosis was poor overall for haemangiosarcoma. However, a common prevailing view of extremely poor prognosis for haemangiosarcoma could be promoting frequent euthanasia at presentation and therefore leading to a self-fulfilling prophecy and low survival times. Further exploration of the potential effect of perceived prognosis is warranted. This study provides valuable information for contextualised care and dialogues with clients in first-opinion practice.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40478827/