Peer-reviewed veterinary case report
Survival times for dogs with nasal sarcoma after radiation therapy
By Sones, Evan et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2013·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Survival times for canine intranasal sarcomas treated with radiation therapy: 86 cases (1996-2011).
- Species:
- dog
Plain-English summary
A group of 86 dogs with intranasal sarcomas (a type of tumor in the nose) were treated with different radiation therapy methods to see how long they could survive. The overall average survival time was about 444 days, but it varied depending on the type of sarcoma and the treatment used. Dogs receiving daily radiation therapy lived the longest, averaging 641 days, while those getting palliative care (focused on comfort rather than cure) had shorter survival times. This suggests that more aggressive radiation therapy can lead to better outcomes for dogs with these tumors.
People also search for: dog nose tumor treatment · intranasal sarcoma survival time · radiation therapy for dogs · dog cancer treatment options
Abstract
Sarcomas comprise approximately one-third of canine intranasal tumors, however few veterinary studies have described survival times of dogs with histologic subtypes of sarcomas separately from other intranasal tumors. One objective of this study was to describe median survival times for dogs treated with radiation therapy for intranasal sarcomas. A second objective was to compare survival times for dogs treated with three radiation therapy protocols: daily-fractionated radiation therapy; Monday, Wednesday, and Friday fractionated radiation therapy; and palliative radiation therapy. Medical records were retrospectively reviewed for dogs that had been treated with radiation therapy for confirmed intranasal sarcoma. A total of 86 dogs met inclusion criteria. Overall median survival time for included dogs was 444 days. Median survival time for dogs with chondrosarcoma (n = 42) was 463 days, fibrosarcoma (n = 12) 379 days, osteosarcoma (n = 6) 624 days, and undifferentiated sarcoma (n = 22) 344 days. Dogs treated with daily-fractionated radiation therapy protocols; Monday, Wednesday and Friday fractionated radiation therapy protocols; and palliative radiation therapy protocols had median survival times of 641, 347, and 305 days, respectively. A significant difference in survival time was found for dogs receiving curative intent radiation therapy vs. palliative radiation therapy (P = 0.032). A significant difference in survival time was also found for dogs receiving daily-fractionated radiation therapy vs. Monday, Wednesday and Friday fractionated radiation therapy (P = 0.0134). Findings from this study support the use of curative intent radiation therapy for dogs with intranasal sarcoma. Future prospective, randomized trials are needed for confirmation of treatment benefits.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23278974/