Peer-reviewed veterinary case report
Susceptibility of Chinese rhesus monkeys to SIV infection.
- Journal:
- AIDS (London, England)
- Year:
- 2005
- Authors:
- Burdo, Tricia H et al.
- Affiliation:
- Department of Neuropharmacology · United States
Abstract
The use of China-derived monkeys in AIDS research has been limited by reports of reduced susceptibility to SIV. We performed a serial passage of SIV in Chinese macaques, which resulted in a viral stock capable of inducing simian AIDS and high levels of replication in these animals. Similar to HIV in humans, SIV pathogenesis in non-human primates is not limited by geographical origin. Chinese macaques are useful in pathogenesis, vaccine, and therapeutic studies in AIDS.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16184046/