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Peer-reviewed veterinary case report

Susceptibility of mice (Mus musculus) to repeated infestation with Amblyomma americanum (Acari: Ixodidae) ticks.

Journal:
Journal of medical entomology
Year:
2004
Authors:
Loftis, Amanda D et al.
Affiliation:
Viral and Rickettsial Zoonoses Branch · United States

Abstract

Laboratory mice, Mus musculus (L.), BALB/c strain, were assessed for their ability to develop resistance to repeated infestation by Amblyomma americanum (L.) ticks. Mice were infested five consecutive times with A. americanum nymphs. No decrease in tick viability was seen after five infestations, suggesting that BALB/c mice do not develop immune-mediated resistance to A. americanum. In contrast, tick viability was significantly reduced in the second infestation of a New Zealand White rabbit, a laboratory animal known to develop resistance to A. americanum.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15605656/