Peer-reviewed veterinary case report
Young Doberman puppy developed liver damage after skin parasite
By Gabriel, A et al.·Published in The Journal of small animal practice·2006·Department of Small Animal Clinical Sciences·View original on PubMed →
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Original publication title: Suspected drug-induced destructive cholangitis in a young dog.
- Species:
- dog
Plain-English summary
A nine-month-old miniature Doberman was brought to the vet because of ongoing jaundice, which is a yellowing of the skin and eyes. After examining the dog, the vet suspected that the jaundice was caused by a reaction to medications the dog had received for a skin condition. The treatments included antibiotics and other medications, which may have led to liver damage. The vet determined that the dog had a condition called drug-induced destructive cholangitis, which affects the liver's bile ducts. The outcome of the treatment was not specified, but addressing the underlying cause is crucial for recovery.
People also search for: dog jaundice causes · miniature Doberman liver problems · drug reactions in dogs
Abstract
A nine-month-old miniature doberman was referred for the evaluation of chronic icterus. History and clinical and histopathological findings were supportive of a diagnosis of drug-induced destructive cholangitis. The main histopathological findings were canalicular, centrilobular cholestasis and ductopenia with moderate inflammatory infiltrate. The dog had received three types of treatment for demodicosis before the onset of jaundice. Amoxicillin-clavulanate, amitraz, milbemycin oxime or an interaction between two of the three drugs may have been responsible for the destructive cholangitis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16761987/