Peer-reviewed veterinary case report
Dog shows delayed nerve problems after organophosphate poisoning
By Schmid, Renee D et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2023·Pet Poison Helpline/SafetyCall International, United States·View original on PubMed →
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Original publication title: Suspected intermediate syndrome in a dog after organophosphate poisoning.
- Species:
- dog
Plain-English summary
A dog showed signs of poisoning after eating an insecticide and developed neurological symptoms about a day later. This condition, known as intermediate syndrome, can happen after organophosphate poisoning. Fortunately, the dog's symptoms improved after receiving a treatment called pralidoxime chloride. Early treatment was key to the dog's recovery, and both dogs that were exposed to the insecticide initially showed signs of poisoning, but only one developed the more serious syndrome.
People also search for: dog organophosphate poisoning treatment · dog neurological symptoms after insecticide · pralidoxime chloride for dogs
Abstract
OBJECTIVE: To discuss the clinical presentation and successful treatment of a suspected case of intermediate syndrome due to organophosphate (OP) poisoning in a dog. CASE SUMMARY: Two dogs presented with acute cholinergic signs after ingesting an OP insecticide containing 50% acephate. Clinical signs consistent with acute cholinergic crisis resolved in both dogs within 24 hours postingestion. One dog developed an onset of neurological signs consistent with intermediate syndrome approximately 24 hours postingestion. This patient's clinical signs resolved with the use of pralidoxime chloride. NEW OR UNIQUE INFORMATION PROVIDED: OP poisoning most commonly presents as an acute cholinergic crisis, with rare instances of animals developing intermediate syndrome. Few reports of successful treatment and recovery from intermediate syndrome exist in the veterinary literature, particularly with instances in which 2 dogs within the same exposure setting were treated for acute cholinergic signs and only 1 progressed to an intermediate syndrome. This report also highlights the importance of early intervention with pralidoxime chloride prior to the onset of aging.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37943072/