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Peer-reviewed veterinary case report

Dog with stomach cancer and low blood sodium linked to hormone

By Thomas, A et al.·Published in Australian veterinary journal·2024·Perth Veterinary Specialists, Australia·View original on PubMed

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Original publication title: Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog.

Species:
dog

Plain-English summary

A 5-year-old male Australian Kelpie was brought in for chronic vomiting and was found to have low sodium and potassium levels due to a suspected condition linked to a stomach tumor. After imaging confirmed a gastric adenocarcinoma, the tumor was surgically removed. Following the surgery, the dog's electrolyte levels quickly returned to normal, and he was doing well six months later with no signs of the tumor returning or any further issues.

People also search for: dog vomiting stomach tumor · Australian Kelpie low sodium treatment · dog gastric adenocarcinoma surgery outcome

Abstract

This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5-year-old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39157893/