Peer-reviewed veterinary case report
Two dogs with kidney tumors causing high red blood cell counts
By Ide, Kaori et al.·Published in The Journal of veterinary medical science·2024·Cooperative Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Suspected renal interstitial cell tumor causing polycythemia in two dogs.
- Species:
- dog
Plain-English summary
Two dogs were diagnosed with a rare type of kidney tumor called renal interstitial cell tumor, which caused them to have high red blood cell counts (polycythemia) due to elevated levels of a hormone called erythropoietin. Both dogs had solitary tumors located in their kidneys, and tests showed that the tumors were benign. After the affected kidneys were surgically removed, both dogs returned to normal health, with their red blood cell counts and hormone levels stabilizing.
People also search for: dog kidney tumor symptoms · polycythemia in dogs · dog kidney surgery recovery
Abstract
Here we report a case series of two dogs diagnosed as renal interstitial cell tumor (RICT) accompanied by elevated serum erythropoietin level and marked polycythemia. RICT is a rare tumor in dogs, originating from renal interstitial cells. While several renal tumors such as renal lymphoma, adenocarcinoma, carcinoma, sarcoma, fibrosarcoma and nephroblastoma may cause polycythemia, polycythemia caused by RICT has never been reported in dogs. The tumors in both dogs were solitary and lied within cortex or cortico-medullary junction. Histopathology revealed spindle-shaped cells suggesting mesenchymal origin, with no mitotic figures suggesting that the tumors in both dogs were benign. Following surgical removal of the affected kidney, serum erythropoietin level and polycythemia normalized in both dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38383003/