Peer-reviewed veterinary case report
Synovial joint tumors with lymph node spread in 2 dogs
By Glahn, Imaine et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2024·University of Veterinary Medicine Vienna·View original on PubMed →
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Original publication title: Synovial myxoma or myxosarcoma? Lymph node metastasis in 2 dogs.
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog was diagnosed with a rare joint tumor called synovial myxoma, which is usually considered benign. However, in this case, the tumor spread to nearby lymph nodes, raising concerns about its behavior. The dog underwent surgery and further tests to examine the tumor and lymph nodes. The findings suggested that this tumor might be more aggressive than previously thought, leading to a recommendation to refer to it as synovial myxosarcoma instead. This case highlights the need for careful evaluation of similar tumors in dogs to ensure proper diagnosis and treatment.
People also search for: dog joint tumor · synovial myxoma treatment · dog lymph node metastasis · signs of dog cancer · mixed-breed dog tumor symptoms
Abstract
Synovial myxoma, a rare joint tumor in dogs, has traditionally been considered benign, acknowledging that local invasion into regional tissues including bone may be present. Given the diagnostic challenges in distinguishing synovial myxoma from other joint lesions through clinical features and diagnostic imaging, definitive diagnosis relies on characteristic gross and histologic features. Within the inner surface of the joint capsule, synovial myxomas form nodules of stellate-to-spindle cells within abundant myxomatous matrix. We present here 2 cases of synovial myxoma with metastasis to regional lymph nodes and compare these 2 cases to 3 cases without evidence of lymph node metastasis. Aside from lymphovascular invasion in one case with metastasis, there were no overt histologic features of the primary tumor to suggest aggressive biologic behavior. The finding of lymph node metastasis warrants reconsideration of the term "synovial myxoma" for this neoplasm. We suggest the term "synovial myxosarcoma," considering that histologic features of the primary tumor do not predict biologic behavior. Our case series highlights the importance of lymph node sampling in suspected synovial myxosarcoma cases as well as thorough histologic examination, emphasizing careful evaluation for lymphovascular invasion.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38828841/