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Peer-reviewed veterinary case report

Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides.

Journal:
Bioorganic & medicinal chemistry letters
Year:
2004
Authors:
Beebe, Xenia et al.
Affiliation:
Infectious Disease Research · United States

Abstract

A series of novel 6-O-arylpropargyl-9-oxime-ketolides was synthesized and evaluated against various pathogens. These new compounds show promising in vitro antibacterial potency and in vivo efficacy against macrolide resistant strains.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15109624/