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Peer-reviewed veterinary case report

Synthesis of benzophenone oxime analogues as inhibitor of secretory phospholipase A(2) with anti-inflammatory activity.

Journal:
Bioorganic & medicinal chemistry letters
Year:
2004
Authors:
Murari, Satish Kumar et al.
Affiliation:
Department of Studies in Biochemistry · India
Species:
rodent

Abstract

The title compound have been synthesized and tested for structure activity relationship for Phospholipase A(2) (PLA(2)) [E.C. 3.1.1.4] enzyme inhibition. The in vitro PLA(2) enzyme inhibitory activity of benzophenone oxime analogue and in vivo anti-inflammatory activity studies using mice are highlighted.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15109625/