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Peer-reviewed veterinary case report

Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria.

Journal:
Chemical communications (Cambridge, England)
Year:
2007
Authors:
Lu, Jun et al.
Affiliation:
Department of Chemistry · Japan

Abstract

A novel and efficient avenue for the preparation of dimeric vancomycins is described, and the dimers exhibited excellent antibacterial activities in the murine infection model.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17299629/