Peer-reviewed veterinary case report
Brain tumor treatment options and outcomes in dogs
By Hu, H et al.·Published in Journal of veterinary internal medicine·2015·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Systematic Review of Brain Tumor Treatment in Dogs.
- Species:
- dog
Plain-English summary
A review of treatment options for brain tumors in dogs found that while various methods exist, there isn't enough consistent data to determine which is best. The study looked at 794 cases and highlighted that treatments like surgery and radiotherapy may not show significant differences in outcomes, and lomustine, a chemotherapy drug, does not appear to be effective. This means that if your dog is diagnosed with a brain tumor, discussing both surgery and radiotherapy with your veterinarian may be beneficial, as the best approach can vary based on individual cases.
People also search for: dog brain tumor treatment options · surgery vs radiotherapy for dogs · lomustine effectiveness in dogs
Abstract
Intracranial neoplasia is commonly diagnosed in dogs and can be treated by a variety of methods, but formal comparisons of treatment efficacy are currently unavailable. This review was undertaken to summarize the current state of knowledge regarding outcome after the treatment of intracranial masses in dogs, with the aim of defining optimal recommendations for owners. This review summarizes data from 794 cases in 22 previously published reports and follows PRISMA guidelines for systematic review. A Pubmed search was used to identify suitable articles. These then were analyzed for quality and interstudy variability of inclusion and exclusion criteria and the outcome data extracted for summary in graphs and tables. There was a high degree of heterogeneity among studies with respect to inclusion and exclusion criteria, definition of survival periods, and cases lost to follow-up making comparisons among modalities troublesome. There is a need for standardized design and reporting of outcomes of treatment for brain tumors in dogs. The available data do not support lomustine as an effective treatment, but also do not show a clear difference in outcome between radiotherapy and surgery for those cases in which the choice is available.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26375164/