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Peer-reviewed veterinary case report

Systemic Amyloidosis Model on Young Mice.

Journal:
Bulletin of experimental biology and medicine
Year:
2017
Authors:
Kozlov, V A et al.
Affiliation:
Department of Medical Biology with a Course of Microbiology and Virology
Species:
rodent

Abstract

Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28243908/