Peer-reviewed veterinary case report
Dog with vomiting had systemic fungal infection and widespread mast
By Matsuda, Kazuya et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Systemic candidiasis and mesenteric mast cell tumor with multiple metastases in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old female miniature dachshund was brought to the vet because she was vomiting and had diarrhea that wouldn't go away. After testing, the vet discovered that she had two serious conditions: a systemic fungal infection caused by Candida (a type of yeast) and a mast cell tumor that had spread to multiple organs, including her liver and lungs. Unfortunately, both conditions are quite severe and can be difficult to treat. The dog’s prognosis would depend on the extent of the cancer and the effectiveness of any treatments, but this case highlights the importance of early detection and intervention for such complex health issues.
People also search for: dog vomiting and diarrhea · mast cell tumor in dogs · Candida infection treatment in dogs
Abstract
A 5-year-old female miniature dachshund presenting with persistent vomiting and diarrhea had two concurrent rare pathological conditions: systemic candidiasis and mesenteric mast cell tumor with multiorgan metastases. Neoplastic mast cells formed mass in the mesentery of the cecal-colonic region and were also found in the liver, spleen, kidneys, lungs, adrenal grands, ovaries, bone marrow and other tissues. The cells had intracytoplasmic granules with metachromasia and were immunohistochemically positive for c-kit and histamine. Granulomatous lesions with fungal organisms were present in the heart, lungs, kidneys, pancreas, subserosal and surrounding adipose tissue of the duodenum, thyroid glands and mesenteric mass, and phagocytosed organisms were detected in the liver and bone marrow. Bacteriologically and immunohistochemically, the fungi were consistent with Candida albicans.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19262039/