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Peer-reviewed veterinary case report

Dog with systemic Candida infection causing spinal inflammation

By Kuwamura, Mitsuru et al.·Published in The Journal of veterinary medical science·2006·Osaka Prefecture University, Japan·View original on PubMed

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Original publication title: Systemic candidiasis in a dog, developing spondylitis.

Species:
dog

Plain-English summary

A 4-year-old male Shiba Inu was brought to the vet because he was in pain and sensitive to touch. A week later, he started having trouble walking and weakness in his back legs. Unfortunately, he passed away 20 days after his initial visit. A postmortem exam revealed a fungal infection (Candida albicans) that had spread throughout his body, causing severe inflammation in his spine and other organs. This case highlights the seriousness of systemic candidiasis, which can lead to significant health issues in dogs.

People also search for: dog back leg weakness · Shiba Inu pain sensitivity · systemic candidiasis in dogs · fungal infection treatment in dogs

Abstract

A 4-year-old male Shiba dog initially presented with pain of an undetermined origin and hypersensitivity to touch. Seven days later, the dog developed ataxia, hind-leg weakness and knuckling. The dog died on 20 days after presentation. Postmortem examination revealed a mass in the body of thoracic vertebra. Histopathologically, the mass consisted of granulomatous inflammation, including fungal organisms that were immunohistochemically positive for Candida albicans. Similar granulomatous lesions were observed in the systemic lymph nodes, kidneys, pancreas, spleen, prostate gland, thyroid glands and heart. This case was diagnosed as systemic candidiasis with spondylitis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17085895/