Peer-reviewed veterinary case report
Systemic candidiasis in four foals.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1994
- Authors:
- Reilly, L K & Palmer, J E
- Affiliation:
- Department of Clinical Studies · United States
- Species:
- horse
Plain-English summary
Four foals were admitted to the neonatal intensive care unit shortly after birth due to serious health issues like trouble adjusting after birth, kidney failure, and severe intestinal problems, along with signs of infection. They stayed in the hospital for 35 to 70 days and received various strong antibiotics, along with other supportive treatments like IV fluids and nutritional support. During their stay, they developed infections that were hard to pinpoint, and tests revealed they had a fungal infection caused by Candida albicans. The three foals that were treated with antifungal medications, either given through an IV or by mouth, responded well and were able to go home.
Abstract
Four foals were admitted to the neonatal intensive care unit in the first 2 days of life with problems related to birth hypoxia (neonatal maladjustment syndrome, renal failure, necrotizing enterocolitis) and sepsis. Foals were hospitalized for an extended period (35 to 70 days) and received treatment with several broad spectrum antimicrobial agents. Invasive monitoring and treatment procedures included intravenous catheterization, urinary catheterization, and parenteral nutritional and ventilatory support. In each foal, infections of undetermined cause developed, and systemic candidiasis was diagnosed after Candida albicans was isolated from specimens obtained from 1 or more internal sites. The 3 foals in which treatment was attempted responded well to IV administration of amphotericin B and/or oral administration of fluconazole, and were discharged from the hospital.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/7961075/