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Peer-reviewed veterinary case report

Neurological decline from ceroid-lipofuscinosis in young Japanese cat

By Nakayama, H et al.·Published in The Journal of veterinary medical science·1993·Department of Veterinary Pathology, Japan·View original on PubMed

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Original publication title: Systemic ceroid-lipofuscinosis in a Japanese domestic cat.

Species:
cat
Stomach & digestionCats

Plain-English summary

An 11-month-old male Japanese domestic cat was euthanized due to severe neurological symptoms, including shivering and trouble walking. A detailed examination of the cat's brain revealed abnormal deposits of a substance called ceroid-lipofuscin, which can cause damage to nerve cells. This condition is known as systemic ceroid-lipofuscinosis, and it can affect various organs, including the liver and spleen. Unfortunately, the cat's condition was serious, and treatment options were not effective in improving its quality of life.

People also search for: cat shivering and difficulty walking · Japanese domestic cat neurological symptoms · ceroid-lipofuscinosis in cats

Abstract

An 11-month-old castrated male Japanese domestic cat was euthanized because of neurological symptoms such as shivering and difficulty of walking. Histopathological examination showed glial proliferation and marked deposition of ceroid-lipofuscin in the neuronal and glial cells of the brain. Ceroid-lipofuscin was deposited also in reticuloendothelial cells of the liver, spleen and some lymph nodes.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8286538/