Peer-reviewed veterinary case report
Systemic fungal infections in three dogs from nonendemic areas
By Pratt, Carmela L et al.·Published in Journal of the American Animal Hospital Association·2012·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Systemic mycosis in three dogs from nonendemic regions.
- Species:
- dog
Plain-English summary
Three dogs were brought in with various health issues linked to serious fungal infections, even though they had not traveled to areas where these infections are common. One dog had chronic skin sores and swollen lymph nodes, another had sudden eye twitching, and the third experienced diarrhea with blood. Two of the dogs were diagnosed with blastomycosis, with one needing surgery to remove an eye before starting treatment with antifungal medications, which helped them recover. Unfortunately, the third dog with histoplasmosis was euthanized without receiving treatment.
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Abstract
Three dogs were examined for clinical signs ultimately attributed to systemic fungal infections. One dog was evaluated for chronic, ulcerated dermal lesions and lymphadenomegaly; one dog was examined for acute onset of unilateral blepharospasm; and one dog had diarrhea and hematochezia. Two of the dogs were diagnosed with blastomycosis (one with disseminated disease and the other with the disease localized to the left eye). The third dog was diagnosed with disseminated histoplasmosis. None of the dogs originated from, or had traveled to, typical regions endemic for these fungal diseases. All diagnoses were established from histopathology and either polymerase chain reaction (PCR) or cytology and culture. The two dogs diagnosed with blastomycosis were treated with either itraconazole or ketoconazole with apparent resolution of the infections. The dog with ocular involvement had an enucleation prior to beginning therapy. The dog diagnosed with histoplasmosis was euthanized without treatment. In patients with characteristic clinical features, systemic fungal infections should still be considered as differential diagnoses regardless of their travel history.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23033460/