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Peer-reviewed veterinary case report

Cat with heart disease symptoms actually had rare blood vessel

By Herrold, E et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2024·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Systemic reactive angioendotheliomatosis mimicking hypertrophic cardiomyopathy in a domestic shorthair cat.

Species:
cat

Plain-English summary

A 2-year-old male domestic shorthair cat suddenly showed neurological signs, including seizures and panting, and was taken to the vet. Initially, he was diagnosed with a heart condition called hypertrophic cardiomyopathy, but his condition worsened, leading to euthanasia. A necropsy revealed he actually had a rare condition called systemic reactive angioendotheliomatosis, which severely affected his heart. This case highlights that certain heart issues in cats can be misdiagnosed, so it's important for vets to consider other possibilities when they see similar symptoms.

People also search for: cat seizures · domestic shorthair heart problems · cat panting and seizures · hypertrophic cardiomyopathy in cats · systemic reactive angioendotheliomatosis in cats

Abstract

A two-year-old, 3.9-kg, male castrated, domestic shorthair cat presented to The Ohio State University Veterinary Medical Center for acute onset neurological signs. During hospitalization, he was diagnosed with an American College of Veterinary Internal Medicine (ACVIM) stage B1 hypertrophic cardiomyopathy phenotype on echocardiogram. His clinical signs acutely worsened, including seizure activity and panting, and he was euthanized. Necropsy revealed the histopathologic diagnosis of systemic reactive angioendotheliomatosis, which notably severely affected the myocardium. In this case report, we present the antemortem diagnostic results and postmortem necropsy results of this rare condition in cats. This case demonstrates that echocardiographic assessment of the heart in cats affected by systemic reactive angioendotheliomatosis may lead to the false diagnosis of hypertrophic cardiomyopathy and thus should be considered as a differential diagnosis in cats with symmetrical left ventricularl wall thickening on echocardiography.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39342861/