Peer-reviewed veterinary case report
T cells direct microglial repair of white matter after stroke.
- Journal:
- Trends in neurosciences
- Year:
- 2021
- Authors:
- Zera, Kristy A & Buckwalter, Marion S
- Affiliation:
- Department of Neurology and Neurological Sciences · United States
- Species:
- rodent
Abstract
A recent paper by Shi et al. defines the role of regulatory T cells (Tregs) in white matter recovery after ischemic stroke. This study elucidates the mechanisms by which Tregs direct microglia to alter their phenotype to support oligodendrogenesis, thereby improving white matter integrity and functional recovery after stroke in mice.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34332802/